Cromocol
Circular Dichroism BioLogic

EKKO - BioLogic

The EKKO by BioLogic heralds a significant advancement in the automated screening of chiral pharmaceuticals. Engineered for efficiency and robustness, this comp

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EKKO - BioLogic

Revolutionizing Chiral Pharmaceutical Screening with EKKO

The EKKO by BioLogic heralds a significant advancement in the automated screening of chiral pharmaceuticals. Engineered for efficiency and robustness, this compact device outmatches traditional CD (circular dichroism) spectrometers, offering a footprint only a quarter of the size of conventional CD instruments with autosamplers. Its unparalleled scanning speed allows for the rapid identification of 96 reactive products in under two minutes, optimizing both human and energy resources. The EKKO’s capability to quickly determine enantiomeric excess (ee) values without the need for transferring solutions makes it an indispensable tool for conducting parallel synthesis directly in the microplate, presenting an effective HPLC alternative. Additionally, its far-UV spectral measurement feature opens new avenues for high throughput screening of protein structures and biotherapeutic development. Suitable for both early-stage research and late-stage QA/QC processes. BioLogic’s EKKO is not just the only CD microplate reader on the market; it’s a pioneering instrument for high throughput screening in the pharmaceutical and biotech industry, as well as academic research.

Technical Specifications
  • CD High Throughput Screening
  • 185-880 nm
  • 96 well readings < 2 minutes
  • Thousands of ee values per hour
  • Noise floor: as low as 0,05 mdeg (1s)
  • Extra-low operation costs
  • ¼ footprint of a conventional CD with autosampler attachment
  • 10 to 100 x faster than HPLC or conventional CD

Documents & Downloads

EKKO - BioLogic - Datasheet PDF Document

Frequently Asked Questions

What makes EKKO by BioLogic unique in chiral pharmaceutical screening?
The EKKO represents a groundbreaking advancement in the automated screening of chiral pharmaceuticals with its ability to conduct rapid and accurate enantiomeric excess (ee) measurements directly in microplates. This compact, efficient device outperforms traditional CD spectrometers by offering a footprint four times smaller and speeds up to 100 times faster, making it a highly valuable tool for both research and QA/QC processes in the pharmaceutical and biotech industries.
How fast can EKKO screen reactive products?
The EKKO has an unparalleled scanning capability, allowing it to identify 96 reactive products in under two minutes. This efficiency significantly optimizes laboratory human and energy resources by allowing the screening of thousands of ee values within an hour.
Can EKKO replace High-Performance Liquid Chromatography (HPLC) in my lab?
Yes, the EKKO is designed to offer an effective alternative to HPLC for enantiomeric excess (ee) measurements. Its capability to quickly determine ee values without the need for solution transfers and its high throughput capacity make it an indispensable tool for conducting parallel synthesis directly in microplates.
What are the key specifications of EKKO?
The EKKO boasts impressive specifications for high throughput screening, including: CD High Throughput Screening Wavelength range: 185-880 nm Capability to read 96 wells in less than 2 minutes Ability to measure thousands of ee values per hour Noise floor as low as 0.05 mdeg (1s) Operating costs are extra-low Only a quarter of the footprint compared to conventional CD spectrometers with autosampler 10 to 100 times faster screening than HPLC or conventional CD
Is EKKO suitable for both research and QA/QC processes?
Yes, the EKKO is versatile and efficient, making it suitable for application in both early-stage research and late-stage QA/QC processes. Its advanced technology ensures precise results, optimizing productivity and reliability across various stages of pharmaceutical and biotechnological research and development.
Does the EKKO offer any additional features for biotherapeutic development?
Indeed, the EKKO features far-UV spectral measurement capability, a critical addition that opens new avenues for high throughput screening of protein structures. This aspect makes the EKKO particularly beneficial for biotherapeutic development, helping researchers identify promising candidates faster and more efficiently.

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